Perturbation type | Gene | Citation | Cancer type | Gene-disease relation |
---|---|---|---|---|
Top gains | KANK2 (Isoform switch) | 20200238 | LIHC | Differentially expressed in LIHC patients compared to expression profiles in heathy controls |
Top gains | WDR83 (Isoform switch) | 20200238 | LIHC | Differentially expressed in LIHC patients compared to expression profiles in heathy controls |
Top losses | HR (Isoform switch) | 20200238 | LIHC | Differentially expressed in LIHC patients compared to expression profiles in heathy controls |
Top losses | RARB (Isoform switch) | 20200238 | LIHC | Differentially expressed in LIHC patients compared to expression profiles in heathy controls |
Top losses | DDX11 (Isoform switch) | 28496001 | LIHC | Potential therapy targets for human hepatocellular carcinoma. |
Top losses | SLAMF7 (Isoform switch) | 20200238 | LIHC | Differentially expressed in LIHC patients compared to expression profiles in heathy controls |
Top cancer-specific gains | EBF2 | 30089500 | LIHC | Differentially expressed in tumor samples compared to normal samples. |
Top cancer-specific gains | ZNF23 | 21965783 | LIHC | ZNF23 mRNA levels increased in the HepG2 cells. |
Top cancer-specific gains | WNT3A | 28902357 | LIHC | Expression of Wnt3a was significantly increased in tumor tissues compared with normal liver tissues.. |
Top losses | AMHR2 | 25945129 | LIHC | AMHR2 was hypermethylated and transcriptionally repressed LIHC as compared to cancer-free tissue. |
Top cancer-specific losses | BMP10 | www.biorxiv.org/content/biorxiv/early/2018/06/08/342204.full.pdf | LIHC | BMP10 was down-regulated in tumor samples of all LIHC stages compared to the controls. |
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