Results of ProfCom job # 8872 - 17u :

ProfCom searches for rules - complex functions - that are overrepresented in your gene set of interest (set A) and simultaneously underrepresented in your reference set of genes (Set B). In the following you find the top enriched complex functions along with information about the annotation data used.

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Top enriched complex functions of degree 1

Column explanations can be found below

N Simulation Distribution,P-value Hypergeometric Distribution, P-value SET A statistics SET A size SET B statistics SET B size Category Code Category Name Genes
1 0.01 4.3e-05 8 46 522 17607 GO:0005576 extracellular region GAS THBS2 SERPINE1 RNASE1 TFF3 IL6 IL8 CXCL12
2 0.01 0.00011 9 46 788 17607 GO:0005509 calcium ion binding S100P MMP1 GAS ANXA10 THBS2 PLS1 LDLR EFHD2 MRC1
3 0.01 0.0015 7 46 706 17607 GO:0005887 integral to plasma membrane TM4SF3 TM4SF4 CEACAM6 CEACAM5 LDLR SLC28A2 MRC1

Details:
Column "Set A statistics" reports the number of genes from the category in the set A, in brackets the size of the set A is given.
Column "Set B statistics" reports the number of genes from the category in the set B (all other genes from the reference set), in brackets the size of the set B is given.
Column "P value" reports the p value computed by simulation procedure or by hypergeometric distribution.
Column "Category code" reports the category code.
Column "Category name" reports the category name.


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