ProfCom, Technische Universitaet Muenchen, Germany

To the web view

Demo Walk-Through

Here's an example how to start a request for profiling of complex functionality. ProfCom aims to identify rules - complex functionality - overrepresented in our gene set of interest (set A) and simultaneously underrepresented in the reference set of genes (Set B).

All in all, you just have to enter a sets of protein or gene identifiers you want to analyze.

Step 1 - Enter genes of interest

In this form you have to insert the IDs of proteins from the first set of proteins. Allmost all common identifiers like gene names, Affymetrix probe codes, UniProt-, RefSeq- or GenBank accessions can be supplied.

You can either specify a file on your computer containing this set of IDs or enter the IDs manually (format: one ID per row or any blanks as delimiter).

Step 2 - Parameterize

Here you can enter any user specific short name or description of the job and adjust the profining algorithm.


Step 3 - Confirm & Submit

The last page gives you a summary of your data and the parameters choosen. Submit the job now with the "SUBMIT" button.


Your results

You can either wait directly for the computation results and if you have entered an email adress you will be informed additionally by email.

View the results of example analyses here (details in data &methods).

Please cite: Antonov AV*, Schmidt T*, Wang Y, Mewes HW. (*equal joint first authors)
ProfCom: a web tool for profiling the complex functionality of gene groups identified from high-throughput data.
Nucleic Acids Res. 2008 May 6.