What is ProfCom?

ProfCom is a web-based tool for the interpretation of genes that were identified to be functionally linked by experiment.

What can ProfCom tell me?

ProfCom automatically generates statistically valid hypotheses / biological models from gene or protein lists supplied by the user. This knowledge can help to improve your understanding of genetic mechanisms involved in biological phenomena under study.

Why Use ProfCom?

Distinguishable features of ProfCom include prepared annotation datasets for model organisms and a novel profiling procedure for identifying enrichment related to complex functional categories.

Additional advantages:

• ProfCom is able to profile complex functions which are constructed as a combination of available annotational terms.
• ProfCom provides insights into the experimental results which are beyond known facts described in normal functional classifications.
• ProfCom can analyze any kind of organisms, annotation types or problem domains with the ProfCom Web Services.
  

Availability

ProfCom is available free of any charge and is open to all users.

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Demo walk through

Examples

Reference:
Antonov AV*, Schmidt T*, Wang Y, Mewes HW. (*equal joint first authors)
ProfCom: a web tool for profiling the complex functionality of gene groups identified from high-throughput data.
Nucleic Acids Res. 2008 May 6.

Feel free to use our other web-based tools for the interpretation of experimental data. Currently you can access the following tools: KEGG spider interpretation of genomics data in the context of the global gene metabolic network. PPI spider interpretation of genomics data in the context of the global protein interaction network. PLIPS an Automatically Collected Database of Protein Lists Reported by Proteomics Studies ProfCom profiling a complex functionality of gene groups GeneSet2MiRNA searching for the signiture of MiRNA regulatory activity in a gene list TICL network-based Interpretation of Compound Lists inferred by high-throughput metabolomics